April 22, 2015

Mesenchymal stem cells, which are found in umbilical cord blood, contain immune modulatory properties. These properties were used to treat collagen-induced arthritis in a recent clinical trial to determine the effectiveness of stem cells collected from cord blood banking, in treating this type of arthritis. Treatment-control mice were injected with 35 mg/kg methotrexate twice weekly, with mesenchymal stem cells taken from cord blood, bone marrow, and adipose tissue. Over the study period, the mice were evaluated. Cytokine expression in the join, serum cytokine levels, degree of inflammation, and regulatory T cells were all observed and evaluated. This process on some level answers the question, “What is stem cell research?” (which we know many people who are new to cord blood banking are asking themselves).

Mice treated with mesenchymal stem cells, which were derived from umbilical cord blood, showed significant improvement in clinical joint score. Histologic examination results showed that joint damage and inflammation was greatly reduced in mice treated with mesenchymal stem cells, versus untreated mice. Joint inflammation overall was significantly suppressed. The cells decreased pro-inflammatory cytokines and upregulated anti-inflammatory cytokines and induced Tregs.

In short, this clinical trial study shows that human cord blood mesenchymal stem cells could potentially be an effective therapeutic approach for treating collagen-induced arthritis. This is why private cord blood banking with CariCord is a viable option to consider during your stages of pregnancy. Cord blood stem cells can be stored in a bank until needed, and can be used to treat a variety of diseases, including arthritis, various types of cancers, leukemia. They are also used for anemia treatment, and more than 80 diseases in all, with more stem cell research revealing new diseases that cord blood can be used to treat.

Those familiar with umbilical cord blood banking know that cord blood, that produces mesenchymal stem cells, can only be collected at the birth of a child, not in early pregnancy stages or after birth. This is why it is important to consider your public and private cord blood banking options during your earlier stages of pregnancy, so that you can make an informed decision of what to do with your child’s cord blood, which could possibly be used in an anemia treatment for your child or a suitable match at some point down the road.

FaceBook  Twitter