May 18, 2015

Cord blood stem cells are currently used to treat more than 80 diseases, with ongoing stem cell research and clinical trials continually finding new treatments and cures. Currently, cord blood is used to treat various types of cancers, leukemias, anemia treatment, and more. For those who are unfamiliar with umbilical cord blood banking and may ask, “What is stem cell research?”, you have come to the right place.

Umbilical cord blood banking is a special process that collects and stores blood from the umbilical cord of a newborn child, as this cord blood is rich in mesenchymal stem cells, which can be used to treat a variety of diseases. The process of cord blood banking is safe and painless for both mother and child, and saves cord blood for future use, as it would otherwise be discarded as medical waste. Because cord blood can only be collected at the birth of a child, it is important for expecting mothers to consider it during their stages of pregnancy.

Umbilical cord matrix mesenchymal stem cells found in both humans and rats possess the ability to control the growth of breast carcinoma cells. Comparative analysis of these two types of stem cells suggest that the cells found in rats are significantly stronger than the cells found in humans when it comes to suppressing the growth of breast cancer. However, one study found that there is a possibility for the human cells to be transformed into much stronger tumoricidal cells by enhancing tumor suppressor gene expression. This means that umbilical cord blood could be a viable option to suppress the growth of breast cancer, allowing for treatment. This was the first study to evaluate and describe the potential use of human cord blood stem cells to create an endogenous tumor suppressor gene for breast cancer treatment.

This is the first study to describe potential use of human UCMSC engineered to express an endogenous tumor suppressor gene for breast cancer treatment. This study clearly indicates that engineering human UCMSC by endogenous tumor suppressor genes can re-enforce UCMSC-dependent tumoricidal ability. It is apparent that generation of more effective human UCMSC requires further studies for efficient cell preparation and long-lasting gene transduction methods.

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