May 25, 2015

When skin wounds occur, the healing process can be quite lengthy and take a period of time, just as stages of pregnancy take time. The dynamic healing process involves inflammation, re-epithelization, granulation, vascularization, and tissue remodeling. The use of stem cell therapy has been utilized to help heal skin wounds that seem to be otherwise delayed in their healing process. Commonly used methods for manipulating stem cell behaviors to help heal skin wounds include the administration of genetic modifications and biochemical cocktails, but these methods are often considered impractical for clinical use, due to their potential side effects. In order to utilize cord blood stem cell therapy in the process of healing skin wounds, it is important to be able to regulate the cell behaviors with predictable methods. The development of a safe and practical way to regulate stem cell migration is key in the skin wound-healing field area of stem cell research.

Arachidonic acid is often released during skin injuries, and scientists engaged in the process of stem cell research have not yet fully studied how arachidonic acid modulates wound repair, if treated with stem cells collected during the process of umbilical cord blood banking. This is why it is important for expecting mothers to consider cord blood banking during their pregnancy stages, because stem cell research is constantly finding new uses for cord blood. A recent study took human umbilical cord blood mesenchymal stem cells and stimulated them with arachidonic acid. This study found that these stem cells, pre-treated with arachidonic acid, enhanced wound filling, re-epithelization, and angiogenesis in a skin wound model utilized on a lab mouse.

In addition to potential skin wound healing, mesenchymal stem cells collected after a mother’s pregnancy stages during the umbilical cord blood banking process can be used for anemia treatment. Cord blood can also be used to treat various types of cancers and leukemias. In all, cord blood can be used to treat more than 80 diseases, with stem cell research continually finding and developing new treatments and therapies that can utilize cord blood. This is why a mother’s choice to bank her newborn’s cord blood, made during her stages of pregnancy, can potentially have a life-altering impact in the future.

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