October 12, 2015

Rotator cuff tendon tear is a common cause of chronic shoulder pain and disability in adults today. However, it is possible that stem cells collected through umbilical cord tissue banking could be feasible in effectively treating this injury. Though cord tissue benefits are not currently available for human treatment, animal models have been promising in many cases.

In one instance, doctors examined the results when using human mesenchymal stem cells taken from umbilical cord tissue to regenerate a full-thickness rotator cuff tendon tear in a rabbit model. This therapy was ultrasound-guided and examined the gross morphology and histology of the tendon that was injected with cord tissue stem cells.

Four weeks after the injection, seven out of ten full-thickness subscapularis tendon tears had improved to the point that they were only partial-thickness tears. The other three remained full-thickness tears. The overall tendon tear size and walking capacity of the rabbit had improved significantly due to the injection of cord tissue stem cells utilizing ultrasound guidance without surgical repair or bioscaffold. The histology revealed that the umbilical cord tissue cells induced regeneration of rotator cuff tendon tear and that the regenerated tissue was predominantly composed of type I collagens.

The results of this study reveal one of the latest potential cord tissue benefits. The injection of these cord tissue cells with the guidance of an ultrasound may be a viable conservative treatment method for full-thickness rotator cuff tendon tear.

Though mesenchymal stem cells collected from cord tissue are shown in this instance and many others to have many benefits, they are not yet authorized for use in human treatments. However, expecting parents can still choose cord tissue banking at the birth of their child, a smart choice as it is very likely that cord tissue treatments will become commonplace in the future. Currently, cord blood banking preserves stem cells that can be used to treat more than 80 diseases. Because new research is ongoing, saving your baby’s cord tissue in addition to cord blood is a solid investment in the future of your child’s health.

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October 09, 2015

CariCord offers both umbilical cord blood and cord tissue banking benefits. Currently, the cells found in cord blood can be used to treat more than eighty known diseases, while the cells in cord tissue are being used in clinical trials and are not yet approved for regular human treatment. Many parents who save their baby’s cord blood also choose to save the umbilical cord tissue, because emerging research could potentially uncover viable treatment options in the not-so-distant future.

Recently in China, doctors utilized mesenchymal stem cells (which are found and collected through umbilical cord tissue banking) in a transplant for a carcinoma patient with radiation myelitis, a rare but dangerous complication that follows therapeutic irradiation to neoplasms when the spinal cord is included in the radiation field. These symptoms usually appear six to twenty-four months after the procedure and there has not been any satisfactory way to treat the symptoms of radiation myelitis. Therefore, doctors turned to mesenchymal cord tissue stem cells to treat the 37-year-old male patient.

After he was first treated, doctors followed up with the patient over periods of two days, one month, nine months, and eighteen months after transplantation using cord tissue cells. The patient was re-admitted for treatment nine months after initial discharge, but proved to be healthy at the eighteen month mark.

Though this is most likely the first time cord tissue cells have been used to treat radiation myelitis, the results have proven to be positive. This shows that stem cells collected from umbilical cord tissue could potentially be a viable future option for treating radiation myelitis in carcinoma patients.

You can read more about this procedure here.

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October 07, 2015

Researchers are continually looking for new ways that stem cells collected by family cord blood services can be utilized to re-create damaged or destroyed cells, which can cure diseases and save lives. This is one of the reasons why parents should save baby cord blood.

Recently, scientists in Australia discovered a method for taking stem cells from human skin into collecting ducts and blood-filtering units known as “nephrons.” These are two of the primary structures found in human kidneys. By using stem cells to form clumps of kidney tissue that are comparable to the kidney structure of a newborn, a critical first step has been taken toward constructing new organs for patients who have suffered kidney failure or damage.

While the kidney’s that have been constructed in a lab are not yet viable for transplanting into patients, they are comparable to the kidney’s of an unborn baby in the first trimester. While a verdict has yet to be reached as to whether or not this kidney tissue will be approved for replacing failed kidneys in human patients, the created kidney tissue is usable now for drug screening. Researchers will also be able to re-create genetic kidney diseases, which will provide insight for future treatment methods.

Until this discovery by Australian scientists, there had been an unsuccessful struggle to get stem cells to form the types of cells in the human kidney, which is why this seemingly small discovery is actually a medical breakthrough that could lead to better understanding of kidney disease and more targeted treatment methods.

Source: http://www.theguardian.com/science/2015/oct/07/stem-cells-from-human-skin-turned-into-kidney-tissue

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October 05, 2015

Doctors in Spain recently announced a groundbreaking trial that will attempt to cure five patients of HIV using stem cells taken from umbilical cord blood. This trial will last for a three year period, in which doctors and researchers will attempt to recreate the case involving the only individual who is known to have been completely cured from the virus. This individual is Timothy Ray Brown, otherwise known as “the Berlin patient.”

The trial is being conducted by the National Organization of Transplants (ONT) of Spain, and will involve stem cells taken from 157 different donors. The ONT has worked with national family cord banks to locate donors who all possess a genetic mutation that allows them to resist the HIV virus.

Brown is an American citizen who was living in Berlin with HIV when he was diagnosed with leukemia in 2006. Mr. Brown needed transplant to treat his leukemia, it was later discovered that his HIV was also cured. It was by pure coincidence that he received stem cells that were able to cure his HIV, but doctors discovered the reason why, and are now trying to duplicate the transplants using stem cells with the same genetic mutation. There are many kinds of leukemia that can be successfully treated using stem cells collected by family cord blood services like CariCord. For more information, consult the parent’s guide to cord blood or the FAQ pages on our website.

Nearly ten years ago, Brown received two stem cell transplants from the bone marrow of the donor. Not only did these transplants make him cancer-free, only traces of the HIV antibodies can be found in his body.

An advantage to stem cells taken from cord blood over those taken from bone marrow is the collection process is non-invasive and pain-free for all parties involved. Research has also shown that cord blood cells can be more flexible than adult bone marrow cells, which makes family cord banking a very appealing option for many families around the world.

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